The Department of Research at ILBS has been established to promote basic and translational research in the area of Hepato-biliary Sciences. It is equipped with sophisticated and latest equipments to carry out the tasks. The primary area of research would be in the field of

• Hepatotropic viruses
• Molecular Virology
• Immunology
• Proteomics
• Genomics
• Tissue/Serum Banking
• Cell Therapy and Regenerative Medicine
• Generation of Biomedical Devices

The department would also encourage research in other areas of basic sciences also which may have direct or indirect relevance to the field of Hepato-biliary Sciences. The department also plans to initiate various fellowships and research associates programme in this area. In order to promote exchange of ideas and foster close working relationship with the prestigious Institutes and Departments, ILBS has already entered into memorandum of understanding with Institutes and Departments within and outside India. The existing faculties of the ILBS have excellent rapport with national and international faculties and ongoing research co-operation which would help kick-start the collaborative research projects.

Research Activities at ILBS

• Hepatitis C Virus-Human Immunodeficiency Virus Coinfection: Immune Mechanisms, Viral Interactions and Pathogenesis
• Early Prediction of Interferon Responsiveness in Hepatitis C patients by using Pharmacogenomic tools
• Identification and Characterization of cellular protein(s) involved in Hepatitis C virus budding
• Role of microRNAs in liver diseases
• Therapeutic role of specific CD4/CD8 T cell responses during sequential Therapy using Tenofovir followed by PEG- interferon to Monotherapy with PEG-interefron in Chronic Hepatitis B Patients
• To study the role of notch signaling pathway in advance liver diseases leading to hepatocellular carcinoma with HBV or HCV infection.
• Use Of Mw As An Adjunct To Antiviral Therapy For Chronic Hepatitis B
• Liver gene therapy by foamy virus vector
• To study the molecular biology of adiponectin and its relevance in patients with non-alcoholic fatty liver diseases
• Immunobiology of interferon responsiveness in HCV infected patients: Role of dendritic cell functionality and suppressors of cytokine signaling proteins- Indo- German Project
• Feasibility, safety and therapeutic efficacy of primary human fetal hepatocyte transplantation for hereditary metabolic disease- Indo- German Project